发明名称 |
Methods of Reducing Apolipoprotein C-III |
摘要 |
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. |
申请公布号 |
US2015216831(A1) |
申请公布日期 |
2015.08.06 |
申请号 |
US201414261160 |
申请日期 |
2014.04.24 |
申请人 |
AMARIN PHARMACEUTICALS IRELAND LIMITED |
发明人 |
Manku Mehar;Osterloh Ian;Wicker Pierre;Braeckman Rene;Soni Paresh;Zakrzewski Joseph S. |
分类号 |
A61K31/232 |
主分类号 |
A61K31/232 |
代理机构 |
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代理人 |
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主权项 |
1. A method of reducing an APOC3 level of a subject on statin therapy and having baseline fasting triglycerides of about 200 mg/dl to about 499 mg/dl, the method comprising administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of ethyl eicosapentaenoate per day. |
地址 |
Dublin IE |