主权项 |
1. A method for determining the presence or absence of kidney cancer in an individual, the method comprising:
a. identifying an individual in need of the prevention or treatment of kidney cancer; b. obtaining a biological sample from the individual and isolating the DNA therefrom; c. determining the methylation level of at least one cytosine within a DNA region in a sample from the individual where the DNA region is at least 90% identical to a sequence selected from the group consisting of SEQ ID NOS: 1, 4, 6, 7, 8, 11, 12, 13, 14, 17, 20, 21, 22, 23, and 24; and d. comparing the methylation level of the at least one cytosine to a threshold value for the at least one cytosine, wherein the threshold value distinguishes between individuals with and without kidney cancer, wherein the comparison of the methylation level to the threshold value is predictive of the presence or absence of kidney cancer in the individual. |