发明名称 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL
摘要 The present invention relates to novel isoxazoline carboxamide derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials.
申请公布号 US2015216172(A1) 申请公布日期 2015.08.06
申请号 US201314430919 申请日期 2013.09.25
申请人 BAYER CROPSCIENCE AG 发明人 Willms Lothar;Schmitt Monika H.;Frenzel Thomas;Haaf Klaus Bernhard;Haeuser-Hahn Isolde;Heinemann Ines;Gatzweiler Elmar;Rosinger Christopher Hugh;Kehne Heinz;Dittgen Jan;Feucht Dieter;Hills Martin;Schmidt Jan Peter;Es-Sayed Mazen;Rinolfi Philippe;Brunet Stephane;Grosjean-Cournoyer Marie-Claire;Lachaise Helene;Vidal Jacky;Coqueron Pierre-Yves;Tuch Arounarith
分类号 A01N43/84;A01N43/82;A01N43/80 主分类号 A01N43/84
代理机构 代理人
主权项 1. Quinoline-isoxazoline derivative of formula (I) in which R1 and R2 independently of one another represent hydrogen; substituted or non-substituted C1-C8-alkyl; C1-C8-haloalkyl; substituted or non-substituted C2-C8-alkenyl; C2-C8-haloalkenyl; substituted or non-substituted C2-C8-alkynyl; C2-C8-haloalkynyl; cyano; isonitrile; nitro; halogen; substituted or non-substituted C1-C8-alkoxy; C1-C8-haloalkoxy; substituted or non-substituted C2-C8-alkenyloxy; C2-C8-haloalkenyloxy, substituted or non-substituted C2-C8-alkynyloxy; C1-C8-haloalkynyloxy; substituted or non-substituted C3-C7-cycloalkyl; substituted or non-substituted C1-C8-alkylsulfanyl; substituted or non-substituted C1-C8-alkylsulfonyl; substituted or non-substituted C1-C8-alkylsulfinyl; amino; substituted or non-substituted C1-C8-alkylamino; substituted or non-substituted di-C1-C8-alkylamino; substituted or non-substituted C1-C8-alkoxycarbonyl; substituted or non-substituted C1-C8-alkylcarbamoyl; substituted or non-substituted di-C1-C8-alkylcarbamoyl; or substituted or non-substituted N—C1-C8-alkyl-C1-C8-alkoxy-carbamoyl; or R1 and R2 can form together with the carbon atom to which they are attached a substituted or non-substituted C3-C7-cycloalkyl; or C3-C7-halocycloalkyl; R3 represents hydrogen; substituted or non-substituted C1-C8-alkyl; C1-C8-haloalkyl; substituted or non-substituted C2-C8-alkenyl; C2-C8-haloalkenyl; substituted or non-substituted C2-C8-alkynyl; C2-C8-haloalkynyl; cyano; isonitrile; nitro; halogen; substituted or non-substituted C1-C8-alkoxy; C1-C8-haloalkoxy; substituted or non-substituted C2-C8-alkenyloxy; C2-C8-haloalkenyloxy, substituted or non-substituted C2-C8-alkynyloxy; C1-C8-haloalkynyloxy; substituted or non-substituted C3-C7-cycloalkyl; substituted or non-substituted C1-C8-alkylsulfanyl; substituted or non-substituted C1-C8-alkylsulfonyl; substituted or non-substituted C1-C8-alkylsulfinyl; amino; substituted or non-substituted C1-C8-alkylamino; substituted or non-substituted di-C1-C8-alkylamino; substituted or non-substituted tri(C1-C8)alkylsilyl-C1-C8-alkyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C2-C8-alkenyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C2-C8-alkynyl; substituted or non-substituted C1-C8-alkoxycarbonyl; substituted or non-substituted C1-C8-alkylcarbamoyl; substituted or non-substituted di-C1-C8-alkylcarbamoyl; or substituted or non-substituted N—C1-C8-alkyl-C1-C8-alkoxy-carbamoyl; substituted or non-substituted aryl; or substituted or non-substituted 5, 6 or 7 membered heterocycle ring with 1 to 3 heteroatoms; or R3 together with R1 or R2 together with the carbon atoms to which they are attached can form a substituted or non-substituted C3-C7 cycloalkyl; C3-C7-halocycloalkyl; or a substituted or non-substituted saturated 5, 6 or 7 membered heterocycle Y represents an oxygen or sulfur atom; Q1, Q2, Q3, Q4, Q5 and Q6 independently of one another represent hydrogen; halogen; nitro; cyano; isonitrile; hydroxyl; amino; sulfanyl; pentafluoro-λ6-sulfanyl; formyl; formyloxy; formylamino; substituted or non-substituted (hydroxyimino)-C1-C8-alkyl; substituted or non-substituted (C1-C8-alkoxyimino)-C1-C8-alkyl; substituted or non-substituted (C2-C8-alkenyloxyimino)-C1-C8-alkyl; substituted or non-substituted (C2-C8-alkynyloxyimino)-C1-C8-alkyl; substituted or non-substituted (benzyloxyimino)-C1-C8-alkyl; carboxy; carbamoyl; N-hydroxycarbamoyl; carbamate; substituted or non-substituted C1-C8-alkyl; C1-C8-haloalkyl; substituted or non-substituted C2-C8-alkenyl; C2-C8-haloalkenyl; substituted or non-substituted C2-C8-alkynyl; C2-C8-haloalkynyl; substituted or non-substituted C1-C8-alkoxy; C1-C8-haloalkoxy; substituted or non-substituted C1-C8-alkylsulfanyl; C1-C8-haloalkylsulfanyl; substituted or non-substituted C1-C8-alkylsulfinyl; C1-C8-haloalkylsulfinyl; substituted or non-substituted C1-C8-alkylsulfonyl; C1-C8-haloalkylsulfonyl; substituted or non-substituted C1-C8-alkylamino; substituted or non-substituted di-C1-C8-alkylamino; substituted or non-substituted C2-C8-alkenyloxy; C2-C8-haloalkenyloxy; substituted or non-substituted C3-C8-alkynyloxy; C2-C8-haloalkynyloxy; substituted or non-substituted C3-C7-cycloalkyl; C3-C7-halocycloalkyl; substituted or non-substituted (C3-C7-cycloalkyl)-C1-C8-alkyl; substituted or non-substituted C4-C7-cycloalkenyl; C4-C7-halocycloalkenyl; substituted or non-substituted (C3-C7-cycloalkyl)-C2-C8-alkenyl; substituted or non-substituted (C3-C7-cycloalkyl)-C2-C8-alkynyl; substituted or non-substituted tri(C1-C8)alkylsilyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C1-C8-alkyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C2-C8-alkenyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C2-C8-alkynyl; substituted or non-substituted C1-C8-alkylcarbonyl; C1-C8-haloalkylcarbonyl; substituted or non-substituted C1-C8-alkylcarbonyloxy; C1-C8-haloalkylcarbonyloxy; substituted or non-substituted C1-C8-alkylcarbonylamino; C1-C8-haloalkylcarbonylamino; substituted or non-substituted C1-C8-alkoxycarbonyl; C1-C8-haloalkoxycarbonyl; substituted or non-substituted C1-C8-alkyloxycarbonyloxy; C1-C8-haloalkoxycarbonyloxy; substituted or non-substituted C1-C8-alkylcarbamoyl; substituted or non-substituted di-C1-C8-alkylcarbamoyl; substituted or non-substituted C1-C8-alkylaminocarbonyloxy; substituted or non-substituted di-C1-C8-alkylaminocarbonyloxy; substituted or non-substituted N-(C1-C8-alkyl)hydroxy carbamoyl; substituted or non-substituted C1-C8-alkoxycarbamoyl; substituted or non-substituted N-(C1-C8-alkyl)-C1-C8-alkoxycarbamoyl; aryl which is optionally substituted by up to 6 identical or different groups Ra; C1-C8-arylalkyl which is optionally substituted by up to 6 identical or different groups Ra; C2-C8-arylalkenyl which is optionally substituted by up to 6 identical or different groups Ra; C2-C8-arylalkynyl which is optionally substituted by up to 6 identical or different groups Ra; aryloxy which is optionally substituted by up to 6 identical or different groups Ra; arylsulfanyl which is optionally substituted by up to 6 identical or different groups Ra; arylamino which is optionally substituted by up to 6 identical or different groups Ra; C1-C8-arylalkyloxy which is optionally substituted by up to 6 identical or different groups Ra; C1-C8-arylalkylsulfanyl which is optionally substituted by up to 6 identical or different groups Ra; C1-C8-arylalkylamino which is optionally substituted by up to 6 identical or different groups Ra; 5, 6 or 7 membered heterocycle with 1 to 3 heteroatoms which is optionally substituted by up to 4 identical or different groups Ra; Ra independently of one another represent halogen; cyano; nitro; substituted or non-substituted C1-C8-alkyl; C1-C8-haloalkyl; substituted or non-substituted C1-C8-alkoxy; C1-C8-haloalkoxy; substituted or non-substituted C1-C8-alkylsulfanyl; C1-C8-haloalkylsulfanyl; substituted or non-substituted tri(C1-C8)alkylsilyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C1-C8-alkyl; substituted or non-substituted (C1-C8-alkoxyimino)-C1-C8-alkyl; or substituted or non-substituted (benzyloxyimino)-C1-C8-alkyl; R4 represents hydrogen, hydroxyl, cyano, substituted or non-substituted C1-C8-alkyl, substituted or non-substituted C2-C8-alkenyl; substituted or non-substituted C2-C8-alkynyl; substituted or non-substituted C3-C7-cycloalkyl, substituted or non-substituted C1-C8-alkoxy; substituted or non-substituted C2-C8-alkenyloxy; substituted or non-substituted C3-C8-alkynyloxy; A represents a direct bond, O, S, NR5, SO, SO2 or a divalent linking group selected from A1 to A6 wherein R6, R7, R8, R9, R10 or R11 independently of one another represent hydrogen; substituted or non-substituted C1-C8-alkyl; C1-C8-haloalkyl; substituted or non-substituted C2-C8-alkenyl; C2-C8-haloalkenyl; substituted or non-substituted C2-C8-alkynyl; C2-C8-haloalkynyl; cyano; isonitrile; nitro; halogen; substituted or non-substituted C1-C8-alkoxy; C1-C8-haloalkoxy; substituted or non-substituted C2-C8-alkenyloxy; C2-C8-haloalkenyloxy, substituted or non-substituted C2-C8-alkynyloxy; C1-C8-haloalkynyloxy; substituted or non-substituted C3-C7-cycloalkyl; substituted or non-substituted C1-C8-alkylsulfanyl; substituted or non-substituted C1-C8-alkylsulfonyl; substituted or non-substituted C1-C8-alkylsulfinyl; amino; substituted or non-substituted C1-C8-alkylamino; substituted or non-substituted di-C1-C8-alkylamino; substituted or non-substituted C1-C8-alkoxycarbonyl; substituted or non-substituted C1-C8-alkylcarbamoyl; substituted or non-substituted di-C1-C8-alkylcarbamoyl; or substituted or non-substituted N—C1-C8-alkyl-C1-C8-alkoxy-carbamoyl; or R6 and R7 can form together with the carbon atom to which they are attached a substituted or non-substituted C3-C7-cycloalkyl; or C3-C7-halocycloalkyl; orR8 and R9 can form together with the carbon atom to which they are attached a substituted or non-substituted C3-C7-cycloalkyl; or C3-C7-halocycloalkyl; orR10 and R11 can form together with the carbon atom to which they are attached a substituted or non-substituted C3-C7-cycloalkyl; or C3-C7-halocycloalkyl; or R13 represents hydrogen, substituted or non-substituted C1-C8-alkyl, C1-C8-haloalkyl; substituted or non-substituted C2-C8-alkenyl; substituted or non-substituted C2-C8-alkynyl; substituted or non-substituted C3-C7-cycloalkyl, substituted or non-substituted C1-C8-alkoxy; substituted or non-substituted C2-C8-alkenyloxy; substituted or non-substituted C3-C8-alkynyloxy; X represents represent hydrogen; halogen; nitro; cyano; isonitrile; hydroxyl; amino; sulfanyl; pentafluoro-λ6-sulfanyl; formyl; formyloxy; formylamino; substituted or non-substituted (hydroxyimino)-C1-C8-alkyl; substituted or non-substituted (C1-C8-alkoxyimino)-C1-C8-alkyl; substituted or non-substituted (C2-C8-alkenyloxyimino)-C1-C8-alkyl; substituted or non-substituted (C2-C8-alkynyloxyimino)-C1-C8-alkyl; substituted or non-substituted (benzyloxyimino)-C1-C8-alkyl; carboxy; carbamoyl; N-hydroxycarbamoyl; carbamate; substituted or non-substituted C1-C8-alkyl; C1-C8-haloalkyl; substituted or non-substituted C2-C8-alkenyl; C2-C8-haloalkenyl; substituted or non-substituted C2-C8-alkynyl; C2-C8-haloalkynyl; substituted or non-substituted C1-C8-alkoxy; C1-C8-haloalkoxy; substituted or non-substituted C1-C8-alkylsulfanyl; C1-C8-haloalkylsulfanyl; substituted or non-substituted C1-C8-alkylsulfinyl; C1-C8-haloalkylsulfinyl; substituted or non-substituted C1-C8-alkylsulfonyl; C1-C8-haloalkylsulfonyl; substituted or non-substituted C1-C8-alkylamino; substituted or non-substituted di-C1-C8-alkylamino; substituted or non-substituted C2-C8-alkenyloxy; C2-C8-haloalkenyloxy; substituted or non-substituted C3-C8-alkynyloxy; C2-C8-haloalkynyloxy; substituted or non-substituted C3-C7-cycloalkyl; C3-C7-halocycloalkyl; substituted or non-substituted (C3-C7-cycloalkyl)-C1-C8-alkyl; substituted or non-substituted C4-C7-cycloalkenyl; C4-C7-halocycloalkenyl; substituted or non-substituted (C3-C7-cycloalkyl)-C2-C8-alkenyl; substituted or non-substituted (C3-C7-cycloalkyl)-C2-C8-alkynyl; substituted or non-substituted tri(C1-C8)alkylsilyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C1-C8-alkyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C2-C8-alkenyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C2-C8-alkynyl; substituted or non-substituted C1-C8-alkylcarbonyl; C1-C8-haloalkylcarbonyl; substituted or non-substituted C1-C8-alkylcarbonyloxy; C1-C8-haloalkylcarbonyloxy; substituted or non-substituted C1-C8-alkylcarbonylamino; C1-C8-haloalkylcarbonylamino; substituted or non-substituted C1-C8-alkoxycarbonyl; C1-C8-haloalkoxycarbonyl; substituted or non-substituted C1-C8-alkyloxycarbonyloxy; C1-C8-haloalkoxycarbonyloxy; substituted or non-substituted C1-C8-alkylcarbamoyl; substituted or non-substituted di-C1-C8-alkylcarbamoyl; substituted or non-substituted C1-C8-alkylaminocarbonyloxy; substituted or non-substituted di-C1-C8-alkylaminocarbonyloxy; substituted or non-substituted N-(C1-C8-alkyl)hydroxy carbamoyl; substituted or non-substituted C1-C8-alkoxycarbamoyl; substituted or non-substituted N-(C1-C8-alkyl)-C1-C8-alkoxycarbamoyl; aryl which is optionally substituted by up to 6 identical or different groups Rb; C1-C8-arylalkyl which is optionally substituted by up to 6 identical or different groups Rb; C2-C8-arylalkenyl which is optionally substituted by up to 6 identical or different groups Rb; C2-C8-arylalkynyl which is optionally substituted by up to 6 identical or different groups Rb; aryloxy which is optionally substituted by up to 6 identical or different groups Rb; arylsulfanyl which is optionally substituted by up to 6 identical or different groups Rb; arylamino which is optionally substituted by up to 6 identical or different groups Rb; C1-C8-arylalkyloxy which is optionally substituted by up to 6 identical or different groups Rb; C1-C8-arylalkylsulfanyl which is optionally substituted by up to 6 identical or different groups Rb; C1-C8-arylalkylamino which is optionally substituted by up to 6 identical or different groups Rb; 5 or 6 member heterocycle with 1 to 3 heteroatoms which is optionally substituted by up to 4 identical or different groups Rb; Rb independently of one another represent halogen; cyano; nitro; substituted or non-substituted C1-C8-alkyl; C1-C8-haloalkyl; substituted or non-substituted C1-C8-alkoxy; C1-C8-haloalkoxy; substituted or non-substituted C1-C8-alkylsulfanyl; C1-C8-haloalkylsulfanyl; substituted or non-substituted tri(C1-C8)alkylsilyl; substituted or non-substituted tri(C1-C8)alkylsilyl-C1-C8-alkyl; substituted or non-substituted (C1-C8-alkoxyimino)-C1-C8-alkyl; or substituted or non-substituted (benzyloxyimino)-C1-C8-alkyl; substituted or non-substituted 5, 6 or 7 membered heterocycle with 1 to 3 heteroatoms; or two Rb together can form together with the carbon atoms to which they are attached a substituted or non-substituted 5, 6 or 7 membered heterocycle; or a substituted or non-substituted 5 or 6 membered carbocycle; or R4 together with A and X can form together with the nitrogen to which A and R4 are attached a substituted or non-substituted 5, 6 or 7 membered heterocycle; and/or a salt and/or N-oxide.
地址 Monheim DE