发明名称 PHARMACEUTICAL COMPOSITION INCLUDING 5-{4-(AMINOSULFONYL)PHENYL}-2,2-DIMETHYL-4-(3-FLUOROPHENYL)-3(2H)-FURANONE AND CAPSULE FORMULATION INCLUDING THE PHARMACEUTICAL COMPOSITION
摘要 The present invention relates to a pharmaceutical composition including (i) the compound of Formula 1 described in the specification or a pharmaceutically acceptable salt thereof, (ii) a pharmaceutically acceptable diluent, and (iii) a pharmaceutically acceptable lubricant. The compound of Formula 1 or pharmaceutically acceptable salt thereof has a 50% volume particle diameter (d(0.5)) of 3 μm to 9 μm. The pharmaceutical composition of the present invention has the advantages of good stability, high dissolution rate, improved content uniformity, and excellent pharmacokinetic properties. Due to these advantages, the pharmaceutical composition of the present invention is effective in treating inflammation or pain.
申请公布号 WO2015115853(A1) 申请公布日期 2015.08.06
申请号 WO2015KR01002 申请日期 2015.01.29
申请人 CRYSTALGENOMICS, INC. 发明人 KIM, BYUNG-HA;AHN, SIK IL;PARK, JAE-YEON;KIM, TAE RYONG;CHO, JOONG MYUNG;RO, SEONGGU
分类号 A61K31/34;A61K9/48;A61K31/255;A61K47/38 主分类号 A61K31/34
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