MICROBIOTA RESTORATION THERAPY (MRT), COMPOSITIONS AND METHODS OF MANUFACTURE

摘要

Microbiota restoration therapy compositions and methods for manufacturing, processing, and/or delivering microbiota restoration therapy compositions are disclosed. An example method for manufacturing a microbiota restoration therapy composition may include collecting a human fecal sample and adding a diluent to the human fecal sample to form a diluted sample. The diluent may include a cryoprotectant. The method may also include mixing the diluted sample with a mixing apparatus and filtering the diluted sample. Filtering may form a filtrate. The method may also include transferring the filtrate to a sample bag and sealing the sample bag.

主权项

1. A microbiota restoration therapy composition, comprising:
a processed human fecal preparation; wherein the processed human fecal preparation includes a fecal sample and a cryoprotectant; and wherein the processed human fecal preparation is pre-screened for bacterial diversity and includes bacteria from six or more different taxonomic families.