发明名称 |
NOVEL 2-PHENYLBENZOFURAN DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PRODUCTION METHOD FOR SAME AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASE COMPRISING SAME AS ACTIVE INGREDIENT |
摘要 |
The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, to a production method for same and to a pharmaceutical composition for preventing or treating an inflammatory disease comprising same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6 and TNF-alpha due to macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease. |
申请公布号 |
WO2015115805(A1) |
申请公布日期 |
2015.08.06 |
申请号 |
WO2015KR00922 |
申请日期 |
2015.01.28 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
LEE, KYEONG;OH, SEI-RYANG;AHN, KYUNG SEOP;KWON, OK-KYOUNG;KIM, DOO-YOUNG;RYU, HYUNG WON;KIM, JUNG HEE;XU, XUEZHEN |
分类号 |
C07D307/78;A61K31/343;A61P29/00;C07D307/77 |
主分类号 |
C07D307/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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