发明名称 NOVEL 2-PHENYLBENZOFURAN DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PRODUCTION METHOD FOR SAME AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASE COMPRISING SAME AS ACTIVE INGREDIENT
摘要 The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, to a production method for same and to a pharmaceutical composition for preventing or treating an inflammatory disease comprising same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6 and TNF-alpha due to macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
申请公布号 WO2015115805(A1) 申请公布日期 2015.08.06
申请号 WO2015KR00922 申请日期 2015.01.28
申请人 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION 发明人 LEE, KYEONG;OH, SEI-RYANG;AHN, KYUNG SEOP;KWON, OK-KYOUNG;KIM, DOO-YOUNG;RYU, HYUNG WON;KIM, JUNG HEE;XU, XUEZHEN
分类号 C07D307/78;A61K31/343;A61P29/00;C07D307/77 主分类号 C07D307/78
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