发明名称 Polymorphic Forms Of Naltrexone
摘要 This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations.
申请公布号 US2015218178(A1) 申请公布日期 2015.08.06
申请号 US201514612904 申请日期 2015.02.03
申请人 Alkermes, Inc. 发明人 Brittain Harry G.;Dickason David A.;Hotz Joyce M.;Lyons Shawn L.;Ramstack J. Michael;Wright Steven G.
分类号 C07D489/08 主分类号 C07D489/08
代理机构 代理人
主权项 1. A polymorphic form of naltrexone benzyl alcohol solvate which is characterized by an X-ray powder diffraction with a characteristic peak at about 5-6° (2θ).
地址 Waltham MA US