发明名称 SYSTEM AND METHOD FOR THERAPEUTIC MANAGEMENT OF OCULAR HYPERTENSION
摘要 One embodiment is directed to a method for treating hypertension within the eye of a patient, comprising: delivering an effective amount of polynucleotide comprising an exogenous receptor genetic material which is expressed in a targeted tissue structure of the eye, wherein the targeted tissue structure has been genetically modified to have light sensitive protein; waiting for a period of time to ensure that sufficient portions of the targeted tissue structure of the eye will express the desired light sensitive protein; and causing controlled mechanical changes to the permeability of the eye by directing light to the targeted tissue structure through a light deliver element optically intercoupled between a light source and the targeted tissue structure of the eye.
申请公布号 US2015217129(A1) 申请公布日期 2015.08.06
申请号 US201514592793 申请日期 2015.01.08
申请人 Circuit Therapeutics, Inc. 发明人 Thomas Griffith Roger;Frazier Shawnalea;Angeley David;Huang Joyce;Andersen Dan
分类号 A61N5/06;A61K38/17;A61K48/00 主分类号 A61N5/06
代理机构 代理人
主权项 1. A method for treating hypertension within the eye of a patient, comprising: a. delivering an effective amount of polynucleotide comprising an exogenous receptor genetic material which is expressed in a targeted tissue structure of the eye, wherein the targeted tissue structure has been genetically modified to have light sensitive protein; b. waiting for a period of time to ensure that sufficient portions of the targeted tissue structure of the eye will express the desired light sensitive protein; and c. causing controlled mechanical changes to the permeability of the eye by directing light to the targeted tissue structure through a light delivery element optically intercoupled between a light source and the targeted tissue structure of the eye.
地址 Menlo Park CA US