发明名称 |
SYSTEM AND METHOD FOR THERAPEUTIC MANAGEMENT OF OCULAR HYPERTENSION |
摘要 |
One embodiment is directed to a method for treating hypertension within the eye of a patient, comprising: delivering an effective amount of polynucleotide comprising an exogenous receptor genetic material which is expressed in a targeted tissue structure of the eye, wherein the targeted tissue structure has been genetically modified to have light sensitive protein; waiting for a period of time to ensure that sufficient portions of the targeted tissue structure of the eye will express the desired light sensitive protein; and causing controlled mechanical changes to the permeability of the eye by directing light to the targeted tissue structure through a light deliver element optically intercoupled between a light source and the targeted tissue structure of the eye. |
申请公布号 |
US2015217129(A1) |
申请公布日期 |
2015.08.06 |
申请号 |
US201514592793 |
申请日期 |
2015.01.08 |
申请人 |
Circuit Therapeutics, Inc. |
发明人 |
Thomas Griffith Roger;Frazier Shawnalea;Angeley David;Huang Joyce;Andersen Dan |
分类号 |
A61N5/06;A61K38/17;A61K48/00 |
主分类号 |
A61N5/06 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating hypertension within the eye of a patient, comprising:
a. delivering an effective amount of polynucleotide comprising an exogenous receptor genetic material which is expressed in a targeted tissue structure of the eye, wherein the targeted tissue structure has been genetically modified to have light sensitive protein; b. waiting for a period of time to ensure that sufficient portions of the targeted tissue structure of the eye will express the desired light sensitive protein; and c. causing controlled mechanical changes to the permeability of the eye by directing light to the targeted tissue structure through a light delivery element optically intercoupled between a light source and the targeted tissue structure of the eye. |
地址 |
Menlo Park CA US |