| 发明名称 |
ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE |
| 摘要 |
<p>Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta- associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.</p> |
| 申请公布号 |
WO2015116923(A1) |
申请公布日期 |
2015.08.06 |
| 申请号 |
WO2015US13754 |
申请日期 |
2015.01.30 |
| 申请人 |
COGNITION THERAPEUTICS, INC. |
发明人 |
RISHTON, GILBERT;CATALANO, SUSAN, M.;LOOK, GARY, C. |
| 分类号 |
A61K31/404;A61K31/405;A61P25/00;A61P25/28 |
主分类号 |
A61K31/404 |
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