| 发明名称 |
AMYLOID-BETA BINDING PROTEINS |
| 摘要 |
The present invention relates to amyloid-beta (Aβ) binding proteins. Antibodies of the invention have high affinity to Aβ(20-42) globulomer or any Aβ form that comprises the globulomer epitope. Method of making and method of using the antibodies of the invention are also provided. |
| 申请公布号 |
US2015218261(A1) |
申请公布日期 |
2015.08.06 |
| 申请号 |
US201514618632 |
申请日期 |
2015.02.10 |
| 申请人 |
AbbVie Deutschland GmbH & Co. KG ;AbbVie Inc. |
发明人 |
Barghorn Stefan;Hillen Heinz;Striebinger Andreas;Giaisi Simone;Ebert Ulrich;Benatuil Lorenzo |
| 分类号 |
C07K16/18;A61K39/395;A61K49/00;A61K47/48 |
主分类号 |
C07K16/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A binding protein comprising:
a first amino acid sequence which is at least 90% identical to SEQ ID NO:2 or SEQ ID NO:3; and a second amino acid sequence which is at least 90% identical to SEQ ID NO:1. |
| 地址 |
Wiesbaden DE |
