发明名称 |
STAPHYLOCOCCUS AUREUS SDRE CNAB DOMAIN AND ITS USE FOR VACCINATION. |
摘要 |
<p>The S.aureus Ser-Asp rich fibrinogen/bone sialoprotein-binding protein contains three CnaB domains, and that the third of these provides significant protection against S.aureus infection. Thus a useful S.aureus vaccine can include a SdrE CnaB domain. Furthermore, the SdrE protein has been shown to be relatively resistant to trypsin digestion, which could be connected to the observation that SdrE contains an isopeptide bond within the third CnaB domain.</p> |
申请公布号 |
MX2015005496(A) |
申请公布日期 |
2015.08.05 |
申请号 |
MX20150005496 |
申请日期 |
2013.10.29 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS SA |
发明人 |
ANDREA GUIDO ORESTE MANETTI;LUIGI FIASCHI;MARCO BECHERELLI;PRACHI DUBAY;MASSIMILIANO BIAGINI |
分类号 |
A61K39/085;C07K14/315;C12N15/00 |
主分类号 |
A61K39/085 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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