| 摘要 |
<p>The invention relates to a process for obtention of myofibroblasts. According to this process: (a) a sample of cells essentially comprising fibroblasts is prepared; and (b) this sample of cells is cultured in a serum-free culture medium. The main purpose addressed by the invention is to obtain a population of myofibroblasts, the characteristics whereof facilitate any study of these cells, and in particular as pure as possible a population of myofibroblasts. Some examples of application of the invention are: identification of biomarkers of myofibroblasts, identification of therapeutic targets, identification and validation of anticancer compounds, and an in vitro model for the screening of pharmaceutical or cosmetic compounds.</p> |
