| 发明名称 |
SUBSTITUTED SULFONAMIDE COMPOUNDS |
| 摘要 |
The invention is concerned with the compounds of formula (I): and salts thereof, wherein X, Y, Z, R1, R2, R3, R3′, R4, R5 and R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of Formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain. |
| 申请公布号 |
EP2900642(A1) |
申请公布日期 |
2015.08.05 |
| 申请号 |
EP20130773658 |
申请日期 |
2013.09.26 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
BROTHERTON-PLEISS, CHRISTINE E.;CHEN, HUIFEN;CHEN, SHAOQING;CHEN, ZHI;ERICKSON,SHAWN DAVID;ESTRADA, ANTHONY;KIM, KYUNGJIN;LI, HONGJU;LOVEY, ALLEN JOHN;LYSSIKATOS, JOSEPH P.;QIAN, YIMIN;SO, SUNG-SAU;WOVKULICH, PETER MICHAEL;YI, LIN |
| 分类号 |
C07D231/18;A61K31/18;A61K31/337;A61K31/415;A61K31/44;A61K31/444;A61K31/50;A61K31/501;A61K31/505;A61K31/506;C07C305/06;C07C311/18;C07D401/04;C07D401/12;C07D403/04 |
主分类号 |
C07D231/18 |
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