| 主权项 |
1. A lens-forming composition suitable for making silicone hydrogel contact lenses according to a curing method based on a spatial limitation of actinic radiation, comprising:
(1) from about 10% to about 50% by weight of at least one hydrophilic amide-type vinylic monomer; (2) from about 10% to about 40% by weight of at least one siloxane-containing (meth)acrylamide of formula (1) in which R is H or CH3 R3 and R4 indeendentl of each other are H C1-C6 alkyl, or a monovalent radical of formula (2) in which Y is a C1-C6 alkylene divalent radical or a C1-C6 alkylene divalent radical containing one or more hydroxyl groups, m is an integer of 0 to 5, p is an integer of 1 to 6, and A1, A2 and A3 independent of each other are C1-C6alkyl, phenyl, benzyl, or a radical of formula (3) in which B1, B2 and B3 independent of each other are C1-C6 alkyl, phenyl, or benzyl, provided that at least one of R3 and R4 is a radical of formula (2), and provided that at least two of A1 A2 and A3 are radicals of formula (3); (3) from about 10% to about 40% by weight of a polysiloxane-containing vinylic macromere of formula (4);
Q-X1-G1-PDMS-G2X2-Q)r (4)in which
r is an integer of 1,G1 and G2 independent of each other is a linear or branched C1-C10 alkylene divalent radical, a divalent radical of alk′-Oqalk- in which q is an integer of from 1 to 5 and alk and alk′ independent of each other is a C1-C6 alkylene divalent radical, or a divalent radical of —R′1—X4-E-X5—R′2— in which R′1 and R′2 independent of each other is a linear or branched C1-C10 alkylene divalent radical or a divalent radical of alk′-Oqalk- as defined above, X4 and X5 independent of each other are a linkage selected from the group consisting of inwhich R′ is H or C1-C8 alkyl, E is an alkyl diradical, a cycloalkyl diradical, an alkylcycloalkyl diradical, an alkylaryl diradical, or an aryl diradical with up to 40 carbon atoms which may have ether, thio, or amine linkages in the main chain,X1 and X2 independent of each other are a linkage selected from the group consisting of a direct bond, in which R′ is H or C1-C8 alkyl,PDMS is a polysiloxane divalent radical of formula (5)
-D1U1-D2U2-D3νω (5)in which ν is 0 or 1, ω is an integer of from 0 to 5, U1 and U2 independent of each other represent a divalent radical of —R′1—X4-E-X5—R′2 as defined above or a divalent radical of alk′-Oqalk- as defined above, D1, D2 and D3 independently of each other are a divalent radical selected from the group consisting of —(CH2CH2O)t—CH2CH2— in which t is an integer of 3 to 40, —CF2—(OCF2)a—(OCF2CF2)b—OCF2— in which a and b independent of each other is an integer of 0 to 10 provided that a+b is a number in the range of 10 to 30, and a divalent group of formula (6) in which R3, R4, R5′, R6, R7, R8, R9 and R10, independently of one another, are C1-C8-alkyl, C1-C4 alkyl- or C1-C4- alkoxy-substituted phenyl, fluoro(C1-C18-alkyl), cyano(C1-C12-alkyl), -alk-(OCH2CH2)n—OR11 in which alk is C1-C6-alkylene divalent radical, R11 is C1-C6 alkyl and n is an integer from 1 to 10, m and p independently of each other are an integer of from 2 to 698 and (m+p) is from 5 to 700, provided that at least one of D1, D2 and D3 is represented by formula (6), andQ is an ethylenically unsaturated group of formula (7) in which Z1 and Z2 independent of each other are a linear or branched C1-C12 alkylene divalent radical, a linear or branched C1-C12 alkylene divalent radical having one or more hydroxyl groups, a radical of —(CH2CH2O)d—CH2CH2 in which d is an integer of 1 to 10, unsubstituted phenylene divalent radical, C1-C4 alkyl or C1-C4 alkoxy substituted phenylene divalent radical or C7-C12 aralkylene divalent radical; A5 is —O— or in which R′ is H or C1-C8 alkyl; q1 and q2 independent of each other are an integer of 0 or 1; R14 is hydrogen, C1-C4 alkyl or halogen; R15 and R16 independent of each other are hydrogen, C1-C4 alkyl, phenyl, carboxy, halogen, or a radical of in which X3 is —O—, as defined above or —S— and R17 is a C1-C12 alkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl or dialkylaminoalkyl radical; (4) from about 0.1% to about 1.3% by weight of a photoinitiator, and (5) from 0 to about 5% by weight of a polymerizable UV-absorbing agent or a polymerizable latent UV-absorbing agent; provided that components (1) to (5) and any additional components add up to 100% by weight, wherein if one or more methacrylate monomers are present in the lens-forming composition, the total amount of the methacrylate monomers is less than about 5% by weight, and wherein the lens forming composition is characterized by having a curing time of less than 30 seconds by a UV light having an UV-intensity of about 4.1 mW/cm2. |
