发明名称 |
RECOMBINANT HUMAN T2 RNASE AND USES THEREOF |
摘要 |
<p>The cloning and heterologous expression of human T2 RNase6PL are disclosed. Further disclosed are methods for preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The methods are effected by administering to the subject a therapeutically effective amount of a RNase6PL ribonuclease or close homologues thereof.</p> |
申请公布号 |
CA2582041(C) |
申请公布日期 |
2015.08.04 |
申请号 |
CA20052582041 |
申请日期 |
2005.09.28 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM |
发明人 |
ROIZ, LEVAVA;SCHWARTZ, BETTY;SMIRNOFF, PATRICIA;SHOSEYOV, ODED |
分类号 |
C12N15/55;A61K31/7088;A61K38/46;A61K48/00;C07K1/22;C12N5/00;C12N9/22;C12N9/99;C12Q1/44 |
主分类号 |
C12N15/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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