| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide a hollow fiber membrane external perfusion type oxygenator capable of improving the effect of suppressing and preventing the adhesion of blood platelets.SOLUTION: The hollow fiber membrane external perfusion type oxygenator encloses in a housing gas exchanging porous hollow fiber membranes 3 comprising a hydrophobic polymer material and allows blood to flow on the outer surface side of the hollow fiber membranes and oxygen-containing gas to flow inside the hollow fiber membranes. The outer surface or outer surface layer 3a of the hollow fiber membranes forming a blood contacting section is coated with a polymer 18 having a repeating unit derived from an alkoxyalkyl (meth) acrylate. The coating of the polymer is formed on the outer surface or outer surface layer by contacting the blood flowing side of the oxygenator with a polymer containing solution with the polymer dissolved in a solvent having a solubility parameter value of 38-47.9 (MPa)and water in sequence after the hollow fiber membrane external perfusion type oxygenator is assembled.</p> |
