发明名称 |
SATURATED NITROGEN AND N-ACYLATED HETEROCYCLES POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA |
摘要 |
<p>The present invention concerns a compound of general formula (I): in which n=0 or 1, R1 represents an optionally substituted alkyl chain, in particular substituted alkyl chain, in particular substituted with fluorine, X is chosen from N and CH, and R2 is chosen from optionally substituted phenyl and benzyl, wherein the heterocycles having 6 vertices comprise one, two or three nitrogen atoms. The present invention also concerns the use of this compound as a medicament, in particular in the treatment of bacterial and mycobacterial infections such as tuberculosis in combination with an antibiotic that is active against bacteria and/or mycobacteria, said compound potentiating the activity of said antibiotic.</p> |
申请公布号 |
SG11201504492U(A) |
申请公布日期 |
2015.07.30 |
申请号 |
SG11201504492U |
申请日期 |
2013.12.20 |
申请人 |
UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 |
发明人 |
WILLAND, NICOLAS;DEPREZ, BENOIT;BAULARD, ALAIN;BRODIN, PRISCILLE;FLIPO, MARION;MAINGOT, LUCIE |
分类号 |
C07D211/16;A61K31/451;A61K31/495;A61P31/04;C07D207/08;C07D211/18;C07D211/22;C07D295/185;C07D401/04 |
主分类号 |
C07D211/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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