发明名称 COMPOUNDS WITH NEURAL PROTECTIVE EFFECT, AND PREPARATION AND USE THEREOF
摘要 The invention generally relates to compounds of formula (I) with neural protective effect, and preparation and uses thereof. The compounds have multiple mechanisms or functions, for example, inhibition of monoamine oxidase and cholinesterase, scavenging of free radicals, and protection of cells such as nerve cells. The compounds can be used for manufacture of medicaments of cell protection, for prevention and/or treatment of monoamine oxidase, cholinesterase and free radicals related diseases, for example, neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and stroke, and free-radical related diseases such as heart disease, myocardial ischemia, diabetes and other cardiovascular and cerebrovascular diseases.
申请公布号 WO2015109935(A1) 申请公布日期 2015.07.30
申请号 WO2015CN00193 申请日期 2015.03.20
申请人 GUANGZHOU MAGPIE PHARMACEUTICAL CO., LTD 发明人 WANG, YUQIANG;YOUDIM, MOUSSA B.H.;SUN, YEWEI;ZHANG, ZAIZUN;ZHANG, GAOXIAO;YU, PEI;YI, PENG;LIANG, MING;LIU, WEI
分类号 C07C251/32;A23L1/30;A61K31/15;A61K31/27;A61K31/4965;A61P1/10;A61P1/16;A61P1/18;A61P3/06;A61P3/10;A61P5/16;A61P7/02;A61P9/00;A61P9/10;A61P9/12;A61P9/14;A61P11/00;A61P11/06;A61P13/12;A61P21/00;A61P21/04;A61P25/08;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P27/06;A61P35/00;A61P37/08;A61P39/06;C07C271/44;C07D241/12 主分类号 C07C251/32
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