DETECTING INDICATIONS OF INTRADIALYTIC MORBID EVENTS BY MEASUREMENT OF RELATIVE BLOOD VOLUME, BLOOD PRESSURE AND HEART RATE

摘要

A method of detecting an indication of a potential intradialytic morbid event (IME) by monitoring a patient's condition during excess fluid removalby ultrafiltration during a hemodialysis treatment includes determining the patient's relative blood volume (RBV), and removing a portion of the volume of excess fluid from blood of the patient at an initial ultrafiltration rate while periodically monitoring a second derivative over time of the relative blood volume (SDRBV). The method then includes continuing to remove excess fluid from blood of the patient at the same ultrafilration rate, or, optionally, incrementally increasing the ultrafiltration rate. The method further includes triggering an alarm for an IME for the patient if the SDRBV is in a range of between a low SDRBV alarm level and a high SDRBV alarm level, and, alternatively or additionally monitoring the patient's normalized blood pressure ratio, and taking a remedial action if the alarm is triggered.

主权项

1. A method of detecting an indication of a potential intradialytic morbid event (IME) by monitoring a patient's condition during excess fluid removal by ultrafiltration during a hemodialysis treatment, the method comprising:
i) establishing an initial ultrafiltration rate of fluid removal; ii) determining the patient's relative blood volume (RBV); iii) removing a portion of the volume of excess fluid from blood of the patient at the initial ultrafiltration rate while periodically monitoring: a second derivative of the relative blood volume over time (SDRBV); iv) continuing to remove excess fluid from blood of the patient at the same ultrafiltration rate, or, optionally, incrementally increasing the ultrafiltration rate; v) if the SDRBV is in a range of between a low SDRBV alarm level and a high SDRBV alarm level, triggering an alarm for a potential IME for the patient; and vi) taking a remedial action if the alarm is triggered.