发明名称 Fcgammariib-specific antibodies and methods of use thereof
摘要 <p>The present invention relates to antibodies or fragments thereof that specifically bind Fc³RIIB, particularly human Fc³RIIB, with greater affinity than said antibodies or fragments thereof bind Fc³RIIA, particularly human Fc³RIIA. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.</p>
申请公布号 IL166843(A) 申请公布日期 2015.07.30
申请号 IL20050166843 申请日期 2005.02.13
申请人 MACROGENICS INC. 发明人
分类号 A61K;A61K39/395;A61P;C07K;C07K16/28;C07K16/32;C07K16/42;C12N;C12P 主分类号 A61K
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