| 发明名称 |
HIGH-THROUGHPUT MOUSE MODEL FOR OPTIMIZING ANTIBODY AFFINITIES |
| 摘要 |
Described herein are compositions (e.g. cells and transgenic animals) and methods relating to engineered Ig loci that permit expression of particular antibodies or antibody segments while still permitting recombination and/or maturation process for antibody optimization. |
| 申请公布号 |
CA2936976(A1) |
申请公布日期 |
2015.07.30 |
| 申请号 |
CA20152936976 |
申请日期 |
2015.01.23 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
ALT, FREDERICK;CHENG, HWEI-LING;TIAN, MING |
| 分类号 |
A01K67/027;C07H21/04;C12N5/07;C12P21/02;C12P21/08 |
主分类号 |
A01K67/027 |
| 代理机构 |
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代理人 |
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