Substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C
摘要
This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)- amides of formula (1) and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
申请公布号
AU2014230814(A1)
申请公布日期
2015.07.30
申请号
AU20140230814
申请日期
2014.03.12
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人
ANDERSKEWITZ, RALF;GRAUERT, MATTHIAS;GRUNDL, MARC;HAEBEL, PETER WILHELM;OOST, THORSTEN;PAUTSCH, ALEXANDER;PETERS, STEFAN;BINDER, FLORIAN;VINTONYAK, VIKTOR