COMPOSITIONS AND METHODS FOR AEROSOL PARTICLE COATING PROCESS USING VOLATILE NON-FLAMMABLE SOLVENTS

摘要

The present teachings provide a method for coating particles containing thermally sensitive biologically active materials encapsulated by uniform thin protective moisture barrier coatings, and processes for applying such coatings efficiently, at ambient temperatures and with minimal agglomeration. The coating formulations can comprise dispersants, adhesion promoters, polymers, and plasticizers dissolved or dispersed in a non-flammable, low boiling point solvent such as methylene chloride that is delivered with an aerosol process to target particles. The present teachings also include the resulting particles.