发明名称 METHOD AND SYSTEM FOR MICROBIOME ANALYSIS
摘要 A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.
申请公布号 US2015211078(A1) 申请公布日期 2015.07.30
申请号 US201514593436 申请日期 2015.01.09
申请人 uBiome, Inc. 发明人 Apte Zachary;Richman Jessica
分类号 C12Q1/68;G06F19/22 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A method for processing a nucleic acid sample, comprising nucleic acid content of a microbiome, from an individual, the method comprising: from a sample handling network, providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a pre-process reagent component and configured to receive a sample from a collection site of the individual; at the sample handling network, receiving the sample container with the sample from the collection site of the individual; at a sample processing module within the sample handling network, generating a nucleic acid sample comprising nucleic acid content of the microbiome and of the individual, wherein the nucleic acid sample has a target sequence associated with the microbiome; at the sample processing module, generating a mixture upon combining the nucleic acid sample with a first synthetic nucleic acid molecule having a first identification sequence and a first concentration and a second synthetic nucleic acid molecule having a second identification sequence and a second concentration; at the sample processing module, generating a sequence dataset based upon sequencing nucleic acid content of the microbiome and of the first and the second synthetic nucleic acid molecule of the mixture; at a processing system within the sample handling network, associating the sequence dataset with the individual based upon identification of the first and the second sequence and the first and the second concentration from the sequence dataset.
地址 San Francisco CA US