发明名称 Nicotinic acid alkyl ester for use in conjunction with retinoic acid therapy
摘要 The invention relates to the use of nicotinic acid alkyl esters, especially myristyl nicotinate, to inhibit side effects associated with retinoic acid therapy. Also a part of the invention is a method for improving skin cell differentiation by administering the nicotinic acid alkyl ester in an amount sufficient to increase expression of caspase 14 and filaggrin. Deficiencies in expression of these molecules can be treated in this way as well.
申请公布号 IL200598(A) 申请公布日期 2015.07.30
申请号 IL20090200598 申请日期 2009.08.26
申请人 UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION;ARIZONA BOARD OF REGENTS A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF THE UNIVERSITY OF ARIZONA 发明人
分类号 A61K 主分类号 A61K
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