AZAHETEROCYCLES AS BIR2 AND/OR BIR3 INHIBITORS

摘要

Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, m, n and q are described in this application, and methods of using said compounds in the treatment of cancer.;

主权项

1. A compound of Formula I: wherein: R1 is selected from H and halogen; R2 is selected from
aryl that optionally may be substituted with C1-6-alkyl, OR4, and halogen,aryl that is fused with C3-7-cycloalkyl, andheteroaryl that optionally may be substituted with C1-6-alkyl; R3 is selected from
C1-6-alkyl that optionally may be substituted with OR4 and aryl,C3-7-cycloalkyl,heterocyclyl, andaryl; R4 is selected from H and C1-6-alkyl; n is 1 or 2; m is 0 or 1; and q is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.