| 发明名称 |
CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE |
| 摘要 |
Particles and conjugates for delivering nucleic acid agents. Compositions containing the particles, the conjugates, or both. Methods of using the particles, the conjugates, and the compositions. |
| 申请公布号 |
US2015209440(A1) |
申请公布日期 |
2015.07.30 |
| 申请号 |
US201514682749 |
申请日期 |
2015.04.09 |
| 申请人 |
Eliasof Scott;Fetzer Oliver S.;Hwang Jungyeon;Lim Soo Patrick;Ng Pei-Sze;Svenson Sonke;Bergstrom Donald E. |
发明人 |
Eliasof Scott;Fetzer Oliver S.;Hwang Jungyeon;Lim Soo Patrick;Ng Pei-Sze;Svenson Sonke;Bergstrom Donald E. |
| 分类号 |
A61K47/48;C12N15/113;A61K31/713 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A particle comprising:
a) a plurality of nucleic acid agent-hydrophobic polyester polymer conjugates, each of which comprises a nucleic acid agent covalently attached to a hydrophobic polyester polymer; b) a plurality of PEG-hydrophobic polyester copolymers; and c) a plurality of cationic moieties. |
| 地址 |
Lexington MA US |
