METHODS AND COMPOSITIONS USED IN TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES
摘要
Methods of treating neuroinflammation by administration of a selective protein C activator, such as recombinant human WE thrombin and optionally one or more of its cofactors are disclosed. Also disclosed are pharmaceutical compositions for use in the treatment of mammals that exhibit symptoms of neurological inflammation. The pharmaceutical compositions and pharmacological dose comprise a safe and effective amount of WE thrombin.
申请公布号
WO2015112547(A1)
申请公布日期
2015.07.30
申请号
WO2015US12172
申请日期
2015.01.21
申请人
OREGON HEALTH & SCIENCE UNIVERSITY;THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人
MCCARTY, OWEN, J.;VERBOUT, NORAH;OFFNER-VANDENBARK, HALINA;TUCKER, ERIK, I.