| 发明名称 |
SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS |
| 摘要 |
The present invention provides compounds of Formula (IX):
or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments. |
| 申请公布号 |
EP2899183(A1) |
申请公布日期 |
2015.07.29 |
| 申请号 |
EP20140195397 |
申请日期 |
2012.10.12 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ORWAT, MICHAEL J.;PINTO, DONALD J.P.;SMITH II, LEON M. |
| 分类号 |
C07D217/26;A61K31/437;A61K31/4375;A61K31/4725;A61P7/02;C07D401/10;C07D401/14;C07D413/14 |
主分类号 |
C07D217/26 |
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