发明名称 |
METHODS FOR USE OF NEURAL STEM CELL COMPOSITIONS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM LESIONS |
摘要 |
Methods for inducing non-embryonic lesioned central nervous system neurons to survive, integrate, extend axons over long distances, induce intra-lesion ingrowth of neurons into the lesion from host tissue and form synapses in vivo. Pluripotent neural stem cells are grafted into the lesioned CNS tissue within a tissue adhesive suspension, optionally in the presence of growth factors. No modification of the neuronal regenerative inhibitory environment of the CNS is necessary. |
申请公布号 |
EP2790711(A4) |
申请公布日期 |
2015.07.29 |
申请号 |
EP20120857504 |
申请日期 |
2012.12.10 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LU, PAUL;TUSZYNSKI, MARK H. |
分类号 |
A61K35/12;A61K35/24;A61K38/18;A61P21/00;A61P25/00 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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