发明名称 |
GENERATING AN IMMUNE RESPONSE BY INDUCING CD40 AND PATTERN RECOGNITION RECEPTORS |
摘要 |
<p>Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing pattern recognition receptor activity, and CD40 activity. Also provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing CD40 activity without prostaglandin E2. Also provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible chimeric molecule comprising a region of a pattern recognition receptor or an adaptor thereof.</p> |
申请公布号 |
EP2076272(B1) |
申请公布日期 |
2015.07.29 |
申请号 |
EP20070844466 |
申请日期 |
2007.10.19 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
SPENCER, DAVID;LAPTEVA, NATALIA |
分类号 |
A61K31/713;A61K38/16;C07H21/00;C07K14/00 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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