Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response
摘要
The present invention provides a compound, that is;
wherein Y, W, Z, R1, R2, R4, R5 and R6 are as defined in the specification.
;The compounds may be administered to treat DP, FP, EP1, TP and/or EP4 receptor-mediated diseases or conditions.
申请公布号
US9090566(B2)
申请公布日期
2015.07.28
申请号
US201213723856
申请日期
2012.12.21
申请人
Allergan, Inc.
发明人
Carling William R.;Martos Jose L.;Kangasmetsa Jussi J.;Wang Jenny W.;Woodward David F.
分类号
C07D231/14
主分类号
C07D231/14
代理机构
代理人
Bass Jonathan Y.
主权项
1. A compound that is a 1-[(5-halo or alkyl or fluoroalkyl or alkoxy-2-{(cycloalkyl or substituted cycloalkyl)oxy}phenyl)methyl]-(5-alkyl or fluoroalkyl)-1H-pyrazole-3-(carboxylic acid or methylene carboxylic acid) or an alkyl or aryl ester or sulfonamide thereof.