Methods and compositions for treating metabolic syndrome

摘要

Provided are methods, compositions, systems, and kits for treating metabolic syndrome or a disorder associated with metabolic syndrome, e.g., obesity, dyslipidemia, and/or a diabetic condition, comprising administering systemically to a subject one or more compounds of the Formula (I) and/or (II): or a pharmaceutically acceptable salt, hydrate, solvate, stereoisomer, polymorph, tautomer, isotopically enriched derivative, or prodrug thereof, wherein, L, R1; R2, Z, X, A and B are defined herein.;

主权项

1. A method of treating a diabetic condition selected from the group consisting of type 2 diabetes mellitus and a complication of type 2 diabetes mellitus in a subject, comprising administering systemically and transdermally to the subject a therapeutically effective amount of a compound selected from the group consisting of: