Self-emulsifying composition of OMEGA3 fatty acid

摘要

This invention provides a self-emulsifying composition comprising 50 to 95% by weight in total of at least one compound selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters; and 5 to 50% by weight of an emulsifier having a hydrophilic lipophilic balance of at least 10. The composition has no or reduced ethanol content, and exhibits excellent self-emulsifying property, dispersibility in the composition, emulsion stability, and absorption property. The composition is adapted for use as a drug.

主权项

1. A self-emulsifying composition comprising:
a) 50 to 95% by weight in total amount of the composition of at least one compound selected from the group consisting of eicosapentaenoic acid, docosahexaenoic acid and their pharmaceutically acceptable salts and esters; b) 1 to 20% by weight in total amount of the composition of a sucrose fatty acid ester as an emulsifier; c) 3 to 40 parts by weight of a glycerin based on 100 parts by weight of said component a); and d) up to 4% by weight of ethanol in total amount of the composition.