| 发明名称 |
Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes |
| 摘要 |
Compositions and methods for treating glaucoma are provided. In particular hydrophilic ester prodrugs and their use to reduce central corneal thickening is provided. |
| 申请公布号 |
US9090595(B2) |
申请公布日期 |
2015.07.28 |
| 申请号 |
US201414185556 |
申请日期 |
2014.02.20 |
| 申请人 |
Allergan, Inc. |
发明人 |
Burk Robert M.;Im Wha Bin |
| 分类号 |
C07D409/14;C07D333/40;C07D409/12;A61K9/00;C07D333/38 |
主分类号 |
C07D409/14 |
| 代理机构 |
|
代理人 |
Bass Jonathan Y. |
| 主权项 |
1. A compound having the formula:wherein;
W is selected from the group consisting of: R2 is independently selected from the group consisting of H, C1-C6 alkyl, C1-C6 hydroxyalkyl, and —OH; R3 is independently H, C1-C6 alkyl, C1-C6hydroxyalkyl, or —OH; and n3 is 0-3. |
| 地址 |
Irvine CA US |
