| 发明名称 | Anti-DLL3 antibodies | ||
| 摘要 | Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | ||
| 申请公布号 | US9089615(B2) | 申请公布日期 | 2015.07.28 |
| 申请号 | US201414466842 | 申请日期 | 2014.08.22 |
| 申请人 | Stemcentrx, Inc. | 发明人 | Stull Robert A.;Saunders Laura;Dylla Scott J.;Foord Orit;Liu David;Torgov Michael;Shao Hui |
| 分类号 | A61K39/395;C07K16/18;C12P21/08;A61K47/48;C07K16/28;C07K16/30;A61K31/5517;G01N33/574;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | Womble Carlyle Sandridge & Rice, LLP | 代理人 | Womble Carlyle Sandridge & Rice, LLP |
| 主权项 | 1. An isolated monoclonal antibody, which specifically binds to an epitope within the DSL domain of a DLL3 protein set forth as SEQ ID NO: 3 or 4, wherein the isolated monoclonal antibody is a chimeric antibody, a CDR-grafted antibody, or a humanized antibody. | ||
| 地址 | South San Francisco CA US | ||