| 发明名称 | Bioactive scaffolds | ||
| 摘要 | Provided are tissue scaffolds colonized by vertebrate cells expressing a transgenic bioactive molecule, where the vertebrate cells are unable to undergo mitosis. Also provided are methods of growing tissue in a mammal and methods of delivering a transgenic bioactive molecule to a tissue of a mammal, using the tissue scaffolds. Additionally, methods of making the tissue scaffolds are provided. | ||
| 申请公布号 | US9089117(B2) | 申请公布日期 | 2015.07.28 |
| 申请号 | US200912322262 | 申请日期 | 2009.01.30 |
| 申请人 | The Feinstein Institute For Medical Research | 发明人 | Grande Daniel A.;Mason James M. |
| 分类号 | A01K67/027;A61K47/48;A61L27/38;A61L27/56;A61K38/18;A61K38/30 | 主分类号 | A01K67/027 |
| 代理机构 | Amster, Rothstein & Ebenstein LLP | 代理人 | Amster, Rothstein & Ebenstein LLP |
| 主权项 | 1. A tissue scaffold comprising mammalian cells which have colonized the scaffold, wherein the mammalian cells are transgenic cells in that they comprise a first transgenic bioactive molecule, and wherein the transgenic cells are treated, after colonization of the scaffold, so that they are unable to undergo mitosis. | ||
| 地址 | Manhasset NY US | ||