发明名称 Neuregulin based methods for treating heart failure
摘要 The present invention features methods of treating patients with chronic heart failure by administering a neuregulin polypeptide within a dosage range which is both effective and safe.
申请公布号 US9089524(B2) 申请公布日期 2015.07.28
申请号 US201013376865 申请日期 2010.06.12
申请人 Zensun (Shanghai) Science & Technology Limited 发明人 Zhou Mingdong
分类号 A61K38/16;A61K38/18;C07K14/475;G06K9/00;H01L27/20 主分类号 A61K38/16
代理机构 Jones Day 代理人 Jones Day
主权项 1. A method for treating or delaying heart failure in a human subject in need thereof, wherein the method comprises administering to the human subject in need thereof a neuregulin 1 protein in an amount: a) from about 0.3 μg to about 2.4 μg/kg/day; b) from about 6 EU to about 48 EU/kg/day; or c) from about 0.04 nmol to about 0.34 nmol/kg/day.
地址 Shanghai CN