发明名称 |
Neuregulin based methods for treating heart failure |
摘要 |
The present invention features methods of treating patients with chronic heart failure by administering a neuregulin polypeptide within a dosage range which is both effective and safe. |
申请公布号 |
US9089524(B2) |
申请公布日期 |
2015.07.28 |
申请号 |
US201013376865 |
申请日期 |
2010.06.12 |
申请人 |
Zensun (Shanghai) Science & Technology Limited |
发明人 |
Zhou Mingdong |
分类号 |
A61K38/16;A61K38/18;C07K14/475;G06K9/00;H01L27/20 |
主分类号 |
A61K38/16 |
代理机构 |
Jones Day |
代理人 |
Jones Day |
主权项 |
1. A method for treating or delaying heart failure in a human subject in need thereof, wherein the method comprises administering to the human subject in need thereof a neuregulin 1 protein in an amount:
a) from about 0.3 μg to about 2.4 μg/kg/day; b) from about 6 EU to about 48 EU/kg/day; or c) from about 0.04 nmol to about 0.34 nmol/kg/day. |
地址 |
Shanghai CN |