| 发明名称 |
4,10-BIS((±)-5-BENZOYL-2,3-DIHYDRO-1H-PYRROLO[1,2-A]PYRROLE-1-CARBONYL)-2,6,8,12-TETRAACETYL-2,4,6,8,10,12-HEXAAZATETRACYCLO[5,5,0,0,0]DODECANE AS ANALGETIC MEANS AND METHOD OF ITS OBTAINING |
| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to a novel chemical substance - 4,10-bis((±)-5-benzoyl-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carbonyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,0,0]dodecane The invention also relates to a method of its obtaining, which consists in the acylation of 2,6,8,12-tetraacetyl-2,4,6,8,10,12- hexaazatetracyclo [5,5,0,0,0]dodecane by chloranhydride 5-benzoyl-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid.EFFECT: novel compound, which has analgetic activity, is obtained.2 cl, 1 tbl, 2 ex |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT FARMAKOLOGII IMENI E.D. GOL'DBERGA" SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK;FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE NAUKI INSTITUT PROBLEM KHIMIKO-EHNERGETICHESKIKH TEKHNOLOGIJ SO RAN |
发明人 |
KRYLOVA SVETLANA GENNAD'EVNA;AMOSOVA EVDOKIJA NAUMOVNA;ZUEVA ELENA PETROVNA;RAZINA TAT'JANA GEORGIEVNA;RYBALKINA OL'GA JUR'EVNA;LOPATINA KSENIJA ALEKSANDROVNA;SYSOLJATIN SERGEJ VIKTOROVICH;KALASHNIKOV ALEKSANDR IVANOVICH;MALYKHIN VALERIJ VIKTOROVICH;DYGAJ ALEKSANDR MIKHAJLOVICH;ZHDANOV VADIM VADIMOVICH |
