| 摘要 |
In methods, compounds, and topical formulations for treatment of inflammatory skin disorders incorporating compounds represented by the formulas below:;;wherein each of R1, R2, and R3 is independently hydrogen, hologen, alkyl, or alkoxy; each of R4 and R5 is independently hydrogen, alkyl, or alkoxy; and each of R6 and R7 is independently hydrogen, nitro, alkyl, or alkoxy;;wherein each of A1, A3, and A4 is independently hydrogen or alkyl; and A2 is independently hydrogen or hydroxy; and;wherein each of B1, B2, and B3 is independently hydrogen, hydroxy, or alkoxy; and each of B4 and B5 is independently hydrogen or alkyl, applying such compounds topically as sprays, mists, aerosols, solutions, lotions, gels, creams, ointments, pastes, unguents, emulsions, and suspensions to treat inflammatory skin disorders and the symptoms associated therewith. |
| 主权项 |
1. A method of treating an inflammatory skin disorder and the symptoms associated therewith, comprising topically administering to the skin of a patient in need of such treatment or prevention a composition comprising:
a therapeutically effective amount of at least one compound selected from the group consisting of brimonidine, xylometazoline, epinephrine, norepinephrine, phenylephrine, and methoxamine, and a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier; wherein the inflammatory skin disorder is not rosacea. |
