THERAPEUTIC COMPOSITIONS COMPRISING RILPIVIRINE HCl AND TENOFOVIR DISOPROXIL FUMARATE

摘要

PROBLEM TO BE SOLVED: To provide therapeutic compositions comprising rilpivirine HCl and tenofovir disoproxil fumarate.SOLUTION: The invention provides multilayer tablets that contain rilpivirine hydrochloride, emtricitabine, and tenofovir disoproxil fumarate. The tablets are useful for the treatment of HIV. In one embodiment, the invention provides a tablet comprising a first layer and a second layer, in which: a) the first layer comprises rilpivirine HCl; b) the second layer comprises tenofovir DF; and c) the tablet further comprises emtricitabine.