发明名称 SOLID ORAL DOSAGE FORM OF IRINOTECAN FOR THE TREATMENT OF CANCER
摘要 The present invention relates to a composition, in particular a solid pharmaceutical composition comprising a compound having the formula I, as a free base or a salt thereof, and a mixture comprising a vehicle and a non-ionic surfactant in an amount sufficient to achieve solubilization of compound (I); and typically wherein the composition is coated with an enteric coating. Such composition is particularly useful in treatment of cancer.
申请公布号 WO2015107131(A1) 申请公布日期 2015.07.23
申请号 WO2015EP50728 申请日期 2015.01.16
申请人 ONCORAL PHARMA APS 发明人 HØJGAARD, BENT
分类号 C07D491/22;A61K31/4745;A61P35/00 主分类号 C07D491/22
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