| 发明名称 |
NUCLEOSIDE PHOSPHONATE SALTS |
| 摘要 |
The present invention relates to compounds and methods for treating viral diseases. Some compounds of the invention are described by Formula I:;wherein M+ is Na+, Li+, K+, Ca2+, Mg2+, or NRcRdReRf+ and Rc, Rd, Re and Rf are each independently hydrogen or C1-5 alkyl, or a stereoisomer, a diastereomer, an enantiomer or racemate thereof. |
| 申请公布号 |
US2015203519(A1) |
申请公布日期 |
2015.07.23 |
| 申请号 |
US201514672816 |
申请日期 |
2015.03.30 |
| 申请人 |
Chimerix, Inc. |
发明人 |
Almond Merrick;Lampert Bernhard;Lanier Ernest Randall;Ware Roy W. |
| 分类号 |
C07F9/6561 |
主分类号 |
C07F9/6561 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A stable crystalline form of a compound having the structure: or a stereoisomer, diastereomer, enantiomer or racemate thereof, wherein M+ is Na+, Li+, K+, Ca2+, Mg2+, or NRcRdReRf+, wherein Rc, Rd, Re and Rf are each independently hydrogen or C1-5 alkyl, and wherein the crystalline form of the compound is greater than 95% pure and retains greater than 95% purity after being kept at about 40° C. for four weeks. |
| 地址 |
Durham NC US |
