FUSION PROTEIN FOR ACTIVATING RTK SIGNAL TRANSMISSION BY MEANS OF LIGHT, AND USE THEREOF

摘要

The present invention relates to a fusion protein for reversibly activating RTK signal transmission by means of light and relates to a use thereof, and the invention provides a fusion protein in which a light induced dimer forming protein is coupled to the C-terminal of a receptor tyrosine kinase (RTK) protein or a modified RTK protein which has been modified so as to eliminate a ligand binding site of the RTK protein or ensure that the ligand does not bind.

主权项

1. A fusion protein in which a light-induced dimerized protein is fused to C-terminus of receptor tyrosine kinase (RTK) or RTK mutant protein whose ligand binding domain is deleted or mutated so as not to bind to a ligand.