| 发明名称 |
INHIBITION OF OXIDATIVE STRESS IN ATRIAL FIBRILLATION |
| 摘要 |
Disclosed herein are pharmaceutical compositions and methods for inhibiting oxidative stress in a subject having atrial or ventricular arrhythmias, ventricular failure or heart failure. The methods include administering an effective amount of a NOX2 inhibitor agent to the subject, wherein said administering is under conditions such that a level of oxidative stress in myocardial tissue is reduced or eliminated. The pharmaceutical compositions include a NOX2 inhibitor agent. |
| 申请公布号 |
US2015203852(A1) |
申请公布日期 |
2015.07.23 |
| 申请号 |
US201414542501 |
申请日期 |
2014.11.14 |
| 申请人 |
Northwestern University |
发明人 |
Arora Rishi |
| 分类号 |
C12N15/113;A61B5/00;A61B5/04;A61B5/046 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of inhibiting oxidative stress in a subject having atrial or ventricular arrhythmias, ventricular failure or heart failure, comprising administering an effective amount of a NOX2 inhibitor agent to the subject, wherein said administering is under conditions such that a level of oxidative stress in myocardial tissue is reduced or eliminated. |
| 地址 |
Evanston IL US |
