| 发明名称 |
TAILORED COMBINATORIAL EPIGENETIC THERAPIES FOR P53 GAIN-OF-FUNCTION TUMORS |
| 摘要 |
The present invention provides compositions and methods for treating and preventing cancer. The invention comprises an inhibitor of epigenetic regulators, including MLLl, MLL2, MOZ, menin, WDR5, or a combination thereof. In one embodiment, the invention provides a personalized method of treating a cancer as dependent upon its epigenetic signature. |
| 申请公布号 |
WO2015108940(A2) |
申请公布日期 |
2015.07.23 |
| 申请号 |
WO2015US11355 |
申请日期 |
2015.01.14 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
BERGER, SHELLEY, L.;HUA, XIANXIN;SAMMONS, MORGAN;ZHU, JIAJUN |
| 分类号 |
A61K31/136 |
主分类号 |
A61K31/136 |
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