发明名称 SPIROCYCLIC MORPHINANS AND THEIR USE
摘要 The application is directed to compounds of Formula I′-A;;and especially to compounds of Formula I-A;;and pharmaceutically acceptable salts and solvates thereof, wherein R1a-R5a, Y, Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I′-A, and especially compounds of Formula I-A, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
申请公布号 US2015203495(A1) 申请公布日期 2015.07.23
申请号 US201514607730 申请日期 2015.01.28
申请人 Purdue Pharma L.P. 发明人 GOEHRING R. Richard;Tafesse Laykea;Youngman Mark A.
分类号 C07D471/10 主分类号 C07D471/10
代理机构 代理人
主权项
地址 Stamford CT US