METHOD AND APPARATUS FOR ACQUISITION OF VOLUMETRIC IMAGING DATA WITHIN AN ANATOMIC STRUCTURE

摘要

Methods, apparatus and devices for providing images based on the optical phase gradients within a biological sample can be provided. In one exemplary embodiment, a tethered and/or untethered capsule can be introduced into a biological specimen to acquire images by illuminating the specimen from at least two different angles, while an objective lens arrangement can relay an image from the illuminated sample to an imaging sensor array. According to one exemplary embodiment of the present disclosure, it is possible to utilize a translational and rotational drive mechanism by which a thin plane of imaging is swept through the sample such that a large volume is imaged over time.