| 发明名称 |
System and Method for Predicting the Immunogenicity of a Peptide |
| 摘要 |
A system, computer readable storage medium and method of predicting the immunogenicity of a peptide are provided. In certain cases the system includes: a) a model of a peptide, a model of a MHCII protein and a model of a T cell receptor; and b) an executable program for: (i) evaluating the strength of intermolecular interactions of a complex containing the peptide, the MHCII protein and the T cell receptor to provide a score that predicts the immunogenicity of the peptide; and (ii) outputting the score. |
| 申请公布号 |
US2015205911(A1) |
申请公布日期 |
2015.07.23 |
| 申请号 |
US201314398965 |
申请日期 |
2013.03.14 |
| 申请人 |
Bayer Healthcare LLC |
发明人 |
Aswad Fred Jullien;Paz Pedro |
| 分类号 |
G06F19/12 |
主分类号 |
G06F19/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A computer system comprising a memory comprising:
a) a model of a peptide, a model of a MHCII protein and a model of a T cell receptor; and b) an executable program for:
(i) evaluating the strength of intermolecular interactions of a complex comprising the peptide, the MHCII protein and the T cell receptor to provide a score that predicts the immunogenicity of the peptide; and(ii) outputting the score. |
| 地址 |
Whippany NJ US |
