HMGB1 VARIANTS AND USES THEREOF

摘要

The present invention relates to HMGB1 variants that maintain HMGB1 wild type chemoattractant function while displaying abolished cytokine and/or chemokine stimulating properties. Such molecules are useful in therapy.

主权项

1. An HMGB1 variant, which is a cell chemoattractant and does not stimulate cytokine and/or chemokine production from a cell or, orthologs, derivatives and fragments thereof.